Regulation of Anthrax Toxin-Specific Antibody Titers by Natural Killer T Cell-Derived IL-4 and IFNγ

Activation of Natural Killer-like T cells (NKT) with the CD1d ligand α-GC leads to enhanced production of anthrax toxin protective Ag (PA)-neutralizing Abs, yet the underlying mechanism for this adjuvant effect is not known. In the current study we examined the role of Th1 and Th2 type responses in...

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Main Authors: Devera, T. Scott, Joshi, Sunil K., Aye, Lindsay M., Lang, Gillian A., Ballard, Jimmy D., Lang, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157475/
https://ncbi.nlm.nih.gov/pubmed/21858226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023817
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