Roflumilast Inhibits Respiratory Syncytial Virus Infection in Human Differentiated Bronchial Epithelial Cells

Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast N-oxide (RNO), alters RSV infection of well-diffe...

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Autori principali: Mata, Manuel, Martinez, Isidoro, Melero, Jose A., Tenor, Herman, Cortijo, Julio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720563/
https://ncbi.nlm.nih.gov/pubmed/23936072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069670
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