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Roflumilast Inhibits Respiratory Syncytial Virus Infection in Human Differentiated Bronchial Epithelial Cells

Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast N-oxide (RNO), alters RSV infection of well-diffe...

詳細記述

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書誌詳細
主要な著者: Mata, Manuel, Martinez, Isidoro, Melero, Jose A., Tenor, Herman, Cortijo, Julio
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720563/
https://ncbi.nlm.nih.gov/pubmed/23936072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069670
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