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ISG15 Is Upregulated in Respiratory Syncytial Virus Infection and Reduces Virus Growth through Protein ISGylation

Human respiratory syncytial virus (RSV), for which neither a vaccine nor an effective therapeutic treatment is currently available, is the leading cause of severe lower respiratory tract infections in children. Interferon-stimulated gene 15 (ISG15) is a ubiquitin-like protein that is highly increase...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: González-Sanz, Rubén, Mata, Manuel, Bermejo-Martín, Jesús, Álvarez, Amparo, Cortijo, Julio, Melero, José A., Martínez, Isidoro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794669/
https://ncbi.nlm.nih.gov/pubmed/26763998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02695-15
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