The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

The catalytic activity of GDP/GTP exchange factors (GEFs) is considered critical to maintain the typically high activity of Rho GTPases found in cancer cells. However, the large number of them has made it difficult to pinpoint those playing proactive, nonredundant roles in tumors. In this work, we h...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Menacho-Márquez, Mauricio, García-Escudero, Ramón, Ojeda, Virginia, Abad, Antonio, Delgado, Pilar, Costa, Clotilde, Ruiz, Sergio, Alarcón, Balbino, Paramio, Jesús M., Bustelo, Xosé R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720258/
https://ncbi.nlm.nih.gov/pubmed/23935450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001615
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