Corticosteroids inhibit complement-induced granulocyte aggregation. A possible mechanism for their efficacy in shock states.

Granulocyte (PMN) aggregation and embolization may underlie complement (C)-mediated organ dysfunction in such syndromes as hemodialysis neutropenia and Purtscher's ischem;c retinopathy. Because of clinical and pathologic parallels, we have further suggested a role for this phenomenon in the genesis...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Hammerschmidt, D E, White, J G, Craddock, P R, Jacob, H S
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 1979
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/438338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109365
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