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Corticosteroids inhibit complement-induced granulocyte aggregation. A possible mechanism for their efficacy in shock states.

Granulocyte (PMN) aggregation and embolization may underlie complement (C)-mediated organ dysfunction in such syndromes as hemodialysis neutropenia and Purtscher's ischem;c retinopathy. Because of clinical and pathologic parallels, we have further suggested a role for this phenomenon in the gen...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hammerschmidt, D E, White, J G, Craddock, P R, Jacob, H S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/438338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109365
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