Controlling immune response and demyelination using highly potent bifunctional peptide inhibitors in the suppression of experimental autoimmune encephalomyelitis

In this study, we investigated the efficacy of new bifunctional peptide inhibitors (BPIs) in suppressing experimental autoimmune encephalomyelitis (EAE) in an animal model. BPI [e.g. proteolipid protein–cyclo(1,8)-CPRGGSVC-NH(2) (PLP-cIBR)] is a conjugate between the PLP(139–151) peptide derived fro...

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Detalhes bibliográficos
Main Authors: Kiptoo, P, Büyüktimkin, B, Badawi, A H, Stewart, J, Ridwan, R, Siahaan, T J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719928/
https://ncbi.nlm.nih.gov/pubmed/23480182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12029
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