Controlling immune response and demyelination using highly potent bifunctional peptide inhibitors in the suppression of experimental autoimmune encephalomyelitis

In this study, we investigated the efficacy of new bifunctional peptide inhibitors (BPIs) in suppressing experimental autoimmune encephalomyelitis (EAE) in an animal model. BPI [e.g. proteolipid protein–cyclo(1,8)-CPRGGSVC-NH(2) (PLP-cIBR)] is a conjugate between the PLP(139–151) peptide derived fro...

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Bibliografski detalji
Glavni autori: Kiptoo, P, Büyüktimkin, B, Badawi, A H, Stewart, J, Ridwan, R, Siahaan, T J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719928/
https://ncbi.nlm.nih.gov/pubmed/23480182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12029
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