Controlling immune response and demyelination using highly potent bifunctional peptide inhibitors in the suppression of experimental autoimmune encephalomyelitis

In this study, we investigated the efficacy of new bifunctional peptide inhibitors (BPIs) in suppressing experimental autoimmune encephalomyelitis (EAE) in an animal model. BPI [e.g. proteolipid protein–cyclo(1,8)-CPRGGSVC-NH(2) (PLP-cIBR)] is a conjugate between the PLP(139–151) peptide derived fro...

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Hauptverfasser: Kiptoo, P, Büyüktimkin, B, Badawi, A H, Stewart, J, Ridwan, R, Siahaan, T J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719928/
https://ncbi.nlm.nih.gov/pubmed/23480182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12029
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