Broad-Spectrum Antimalarial Activity of Peptido Sulfonyl Fluorides, a New Class of Proteasome Inhibitors

Despite declining numbers of cases and deaths, malaria remains a major public health problem in many parts of the world. Today, case management relies heavily on a single class of antimalarial compounds: artemisinins. Hence, development of resistance against artemisinins may destroy current malaria...

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Main Authors: Tschan, Serena, Brouwer, Arwin J., Werkhoven, Paul R., Jonker, Anika M., Wagner, Lena, Knittel, Sarah, Aminake, Makoah Nigel, Pradel, Gabriele, Joanny, Fanny, Liskamp, Rob M. J., Mordmüller, Benjamin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Experimental Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719782/
https://ncbi.nlm.nih.gov/pubmed/23689711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00742-12
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