Optimization of a Ligase Detection Reaction-Fluorescent Microsphere Assay for Characterization of Resistance-Mediating Polymorphisms in African Samples of Plasmodium falciparum

Genetic polymorphisms in the malaria parasite Plasmodium falciparum mediate alterations in sensitivity to important antimalarial drugs. Surveillance for these polymorphisms is helpful in assessing the prevalence of drug resistance and designing strategies for malaria control. Multiple methods are av...

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Autori principali: LeClair, Norbert P., Conrad, Melissa D., Baliraine, Frederick N., Nsanzabana, Christian, Nsobya, Samuel L., Rosenthal, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Parasitology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719660/
https://ncbi.nlm.nih.gov/pubmed/23720790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00904-13
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