Optimization of a Ligase Detection Reaction-Fluorescent Microsphere Assay for Characterization of Resistance-Mediating Polymorphisms in African Samples of Plasmodium falciparum

Genetic polymorphisms in the malaria parasite Plasmodium falciparum mediate alterations in sensitivity to important antimalarial drugs. Surveillance for these polymorphisms is helpful in assessing the prevalence of drug resistance and designing strategies for malaria control. Multiple methods are av...

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Detalles Bibliográficos
Main Authors: LeClair, Norbert P., Conrad, Melissa D., Baliraine, Frederick N., Nsanzabana, Christian, Nsobya, Samuel L., Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Parasitology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719660/
https://ncbi.nlm.nih.gov/pubmed/23720790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00904-13
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