Shiga Toxin 2 Reduces Complement Inhibitor CD59 Expression on Human Renal Tubular Epithelial and Glomerular Endothelial Cells

Infections with enterohemorrhagic Escherichia coli (EHEC) are a primary cause of hemolytic-uremic syndrome (HUS). Recently, Shiga toxin 2 (Stx2), the major virulence factor of EHEC, was reported to interact with complement, implying that the latter is involved in the pathogenesis of EHEC-induced HUS...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ehrlenbach, Silvia, Rosales, Alejandra, Posch, Wilfried, Wilflingseder, Doris, Hermann, Martin, Brockmeyer, Jens, Karch, Helge, Satchell, Simon C., Würzner, Reinhard, Orth-Höller, Dorothea
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2013
विषय:
Host Response and Inflammation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719559/
https://ncbi.nlm.nih.gov/pubmed/23690395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01079-12
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