Shiga Toxin 2a Binds to Complement Components C3b and C5 and Upregulates Their Gene Expression in Human Cell Lines

Enterohemorrhagic Escherichia coli (EHEC) infections can cause EHEC-associated hemolytic uremic syndrome (eHUS) via its main virulent factor, Shiga toxins (Stxs). Complement has been reported to be involved in the progression of eHUS. The aim of this study was to investigate the interactions of the...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Kellnerová, Sára, Chatterjee, Sneha, Bayarri-Olmos, Rafael, Justesen, Louise, Talasz, Heribert, Posch, Wilfried, Kenno, Samyr, Garred, Peter, Orth-Höller, Dorothea, Grasse, Marco, Würzner, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824702/
https://ncbi.nlm.nih.gov/pubmed/33374102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13010008
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