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Role of cis-Acting Sites in Stimulation of the Phage λ P(RM) Promoter by CI-Mediated Looping

The lysogenic state of phage λ is maintained by the CI repressor. CI binds to three operators each in the right operator (O(R)) and left operator (O(L)) regions, which lie 2.4 kb apart. At moderate CI levels, the predominant binding pattern is two dimers of CI bound cooperatively at each regulatory...

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Detalhes bibliográficos
Main Authors: Michalowski, Christine B., Little, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719544/
https://ncbi.nlm.nih.gov/pubmed/23708136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02148-12
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