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Role of cis-Acting Sites in Stimulation of the Phage λ P(RM) Promoter by CI-Mediated Looping

The lysogenic state of phage λ is maintained by the CI repressor. CI binds to three operators each in the right operator (O(R)) and left operator (O(L)) regions, which lie 2.4 kb apart. At moderate CI levels, the predominant binding pattern is two dimers of CI bound cooperatively at each regulatory...

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Hlavní autoři: Michalowski, Christine B., Little, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719544/
https://ncbi.nlm.nih.gov/pubmed/23708136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02148-12
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