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Sequence Tolerance of the Phage λ P(RM) Promoter: Implications for Evolution of Gene Regulatory Circuitry

Much of the gene regulatory circuitry of phage λ centers on a complex region called the O(R) region. This ∼100-bp region is densely packed with regulatory sites, including two promoters and three repressor-binding sites. The dense packing of this region is likely to impose severe constraints on its...

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Detalhes bibliográficos
Main Authors: Michalowski, Christine B., Short, Megan D., Little, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529058/
https://ncbi.nlm.nih.gov/pubmed/15547271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.23.7988-7999.2004
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