Site-specific inter-strand cross-links of DNA duplexes

We report the development of technology that allows inter-strand coupling across various positions within one turn of DNA. Four 2′-modified nucleotides were synthesized as protected phosphoramidites and incorporated into DNA oligonucleotides. The modified nucleotides contain either 5-atom or 16-atom...

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Bibliographic Details
Main Authors: Ye, Miao, Guillaume, Johan, Liu, Yu, Sha, Ruojie, Wang, Risheng, Seeman, Nadrian C., Canary, James W.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719409/
https://ncbi.nlm.nih.gov/pubmed/23894693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC21775A
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