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Site-specific inter-strand cross-links of DNA duplexes
We report the development of technology that allows inter-strand coupling across various positions within one turn of DNA. Four 2′-modified nucleotides were synthesized as protected phosphoramidites and incorporated into DNA oligonucleotides. The modified nucleotides contain either 5-atom or 16-atom...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719409/ https://ncbi.nlm.nih.gov/pubmed/23894693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC21775A |
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