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Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression
Cell division requires the coordination of critical protein kinases and phosphatases. Greatwall (Gwl) kinase activity inactivates PP2A-B55 at mitotic entry to promote the phosphorylation of cyclin B–Cdk1 substrates, but how Gwl is regulated is poorly understood. We found that the subcellular localiz...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718974/ https://ncbi.nlm.nih.gov/pubmed/23857770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211141 |
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