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Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila

Mutations in the Drosophila gene greatwall cause improper chromosome condensation and delay cell cycle progression in larval neuroblasts. Chromosomes are highly undercondensed, particularly in the euchromatin, but nevertheless contain phosphorylated histone H3, condensin, and topoisomerase II. Cells...

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Autors principals: Yu, Jiangtao, Fleming, Shawna L., Williams, Byron, Williams, Erika V., Li, ZeXiao, Somma, Patrizia, Rieder, Conly L., Goldberg, Michael L.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171981/
https://ncbi.nlm.nih.gov/pubmed/14970188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310059
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