Bypassing the Greatwall–Endosulfine Pathway: Plasticity of a Pivotal Cell-Cycle Regulatory Module in Drosophila melanogaster and Caenorhabditis elegans

In vertebrates, mitotic and meiotic M phase is facilitated by the kinase Greatwall (Gwl), which phosphorylates a conserved sequence in the effector Endosulfine (Endos). Phosphorylated Endos inactivates the phosphatase PP2A/B55 to stabilize M-phase-specific phosphorylations added to many proteins by...

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Bibliografiske detaljer
Main Authors: Kim, Min-Young, Bucciarelli, Elisabetta, Morton, Diane G., Williams, Byron C., Blake-Hodek, Kristina, Pellacani, Claudia, Von Stetina, Jessica R., Hu, Xiaoqian, Somma, Maria Patrizia, Drummond-Barbosa, Daniela, Goldberg, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2012
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416000/
https://ncbi.nlm.nih.gov/pubmed/22649080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140574
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