Structure-specific endonucleases Xpf and Mus81 play overlapping but essential roles in DNA repair by homologous recombination

DNA double-strand breaks (DSBs) occur frequently during replication in sister chromatids, and are dramatically increased when cells are exposed to chemotherapeutic agents including camptothecin. Such DSBs are efficiently repaired specifically by homologous recombination (HR) with the intact sister c...

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Main Authors: Kikuchi, Koji, Narita, Takeo, Thanh Van, Pham, Iijima, Junko, Hirota, Kouji, Keka, Islam Shamima, Mohiuddin, Okawa, Katsuya, Hori, Tetsuya, Fukagawa, Tatsuo, Essers, Jeroen, Kanaar, Roland, Whitby, Matthew C., Sugasawa, Kaoru, Taniguchi, Yoshihito, Kitagawa, Katsumi, Takeda, Shunichi
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718858/
https://ncbi.nlm.nih.gov/pubmed/23576554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3154
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