Hepatic Cannabinoid Receptor Type 1 Mediates Alcohol-Induced Regulation of Bile Acid Enzyme Genes Expression Via CREBH

Bile acids concentration in liver is tightly regulated to prevent cell damage. Previous studies have demonstrated that deregulation of bile acid homeostasis can lead to cholestatic liver disease. Recently, we have shown that ER-bound transcription factor Crebh is a downstream effector of hepatic Cb1...

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Detalhes bibliográficos
Main Authors: Chanda, Dipanjan, Kim, Yong-Hoon, Li, Tiangang, Misra, Jagannath, Kim, Don-Kyu, Kim, Jung Ran, Kwon, Joseph, Jeong, Won-Il, Ahn, Sung-Hoon, Park, Tae-Sik, Koo, Seung-Hoi, Chiang, John Y L., Lee, Chul-Ho, Choi, Hueng-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718807/
https://ncbi.nlm.nih.gov/pubmed/23894352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068845
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