Hepatic Cannabinoid Receptor Type 1 Mediates Alcohol-Induced Regulation of Bile Acid Enzyme Genes Expression Via CREBH

Bile acids concentration in liver is tightly regulated to prevent cell damage. Previous studies have demonstrated that deregulation of bile acid homeostasis can lead to cholestatic liver disease. Recently, we have shown that ER-bound transcription factor Crebh is a downstream effector of hepatic Cb1...

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Autors principals: Chanda, Dipanjan, Kim, Yong-Hoon, Li, Tiangang, Misra, Jagannath, Kim, Don-Kyu, Kim, Jung Ran, Kwon, Joseph, Jeong, Won-Il, Ahn, Sung-Hoon, Park, Tae-Sik, Koo, Seung-Hoi, Chiang, John Y L., Lee, Chul-Ho, Choi, Hueng-Sik
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718807/
https://ncbi.nlm.nih.gov/pubmed/23894352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068845
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