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In Vivo Neutralization of α-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (V(H)Hs) and a V(H)H-Fc Antibody
Small recombinant antibody fragments (e.g. scFvs and V(H)Hs), which are highly tissue permeable, are being investigated for antivenom production as conventional antivenoms consisting of IgG or F(ab’)(2) antibody fragments do not effectively neutralize venom toxins located in deep tissues. However, a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718736/ https://ncbi.nlm.nih.gov/pubmed/23894495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069495 |
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