Neutralization of Clostridium difficile Toxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain

Clostridium difficile is a leading cause of nosocomial infection in North America and a considerable challenge to healthcare professionals in hospitals and nursing homes. The Gram-positive bacterium produces two high molecular weight exotoxins, toxin A (TcdA) and toxin B (TcdB), which are the major...

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Bibliografische gegevens
Hoofdauteurs: Hussack, Greg, Arbabi-Ghahroudi, Mehdi, van Faassen, Henk, Songer, J. Glenn, Ng, Kenneth K.-S., MacKenzie, Roger, Tanha, Jamshid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058971/
https://ncbi.nlm.nih.gov/pubmed/21216961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198754
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