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Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile
Clostridium difficile infection is a serious and highly prevalent nosocomial disease in which the two large, Rho-glucosylating toxins TcdA and TcdB are the main virulence factors. We report for the first time crystal structures revealing how neutralizing and non-neutralizing single-domain antibodies...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900976/ https://ncbi.nlm.nih.gov/pubmed/24311789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505917 |
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