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Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease

Clostridium difficile is a leading cause of death from gastrointestinal infections in North America. Antibiotic therapy is effective, but the high incidence of relapse and the rise in hypervirulent strains warrant the search for novel treatments. Surface layer proteins (SLPs) cover the entire C. dif...

詳細記述

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書誌詳細
出版年:Appl Microbiol Biotechnol
主要な著者: Kandalaft, Hiba, Hussack, Greg, Aubry, Annie, van Faassen, Henk, Guan, Yonghong, Arbabi-Ghahroudi, Mehdi, MacKenzie, Roger, Logan, Susan M., Tanha, Jamshid
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768215/
https://ncbi.nlm.nih.gov/pubmed/25936376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-015-6594-1
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