Sulfadiazine resistance in Toxoplasma gondii: no involvement of overexpression or polymorphisms in genes of therapeutic targets and ABC transporters

Several treatment failures have been reported for the treatment of toxoplasmic encephalitis, chorioretinitis, and congenital toxoplasmosis. Recently we found three Toxoplasma gondii strains naturally resistant to sulfadiazine and we developed in vitro two sulfadiazine resistant strains, RH-R(SDZ) an...

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Main Authors: Doliwa, Christelle, Escotte-Binet, Sandie, Aubert, Dominique, Sauvage, Virginie, Velard, Frédéric, Schmid, Aline, Villena, Isabelle
格式: Artigo
語言:Inglês
出版: EDP Sciences 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718540/
https://ncbi.nlm.nih.gov/pubmed/23707894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2013020
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