Sulfadiazine resistance in Toxoplasma gondii: no involvement of overexpression or polymorphisms in genes of therapeutic targets and ABC transporters

Several treatment failures have been reported for the treatment of toxoplasmic encephalitis, chorioretinitis, and congenital toxoplasmosis. Recently we found three Toxoplasma gondii strains naturally resistant to sulfadiazine and we developed in vitro two sulfadiazine resistant strains, RH-R(SDZ) an...

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Main Authors: Doliwa, Christelle, Escotte-Binet, Sandie, Aubert, Dominique, Sauvage, Virginie, Velard, Frédéric, Schmid, Aline, Villena, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado: EDP Sciences 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718540/
https://ncbi.nlm.nih.gov/pubmed/23707894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2013020
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