Sulfadiazine resistance in Toxoplasma gondii: no involvement of overexpression or polymorphisms in genes of therapeutic targets and ABC transporters

Several treatment failures have been reported for the treatment of toxoplasmic encephalitis, chorioretinitis, and congenital toxoplasmosis. Recently we found three Toxoplasma gondii strains naturally resistant to sulfadiazine and we developed in vitro two sulfadiazine resistant strains, RH-R(SDZ) an...

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Detalhes bibliográficos
Main Authors: Doliwa, Christelle, Escotte-Binet, Sandie, Aubert, Dominique, Sauvage, Virginie, Velard, Frédéric, Schmid, Aline, Villena, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: EDP Sciences 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718540/
https://ncbi.nlm.nih.gov/pubmed/23707894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2013020
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