Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leucocyte genotoxicity

Ataxia-telangiectasia (A-T) is a genetic disorder associated with high incidence of B cell lymphoma. Using an A-T mouse model, we compared lymphoma incidence in several isogenic mouse colonies harboring different bacterial communities, finding that intestinal microbiota are a major contributor to di...

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Hlavní autoři: Yamamoto, Mitsuko L., Maier, Irene, Dang, Angeline Tilly, Berry, David, Liu, Jared, Ruegger, Paul M., Yang, Jiue-in, Soto, Phillip A., Presley, Laura L., Reliene, Ramune, Westbrook, Aya M., Wei, Bo, Loy, Alexander, Chang, Christopher, Braun, Jonathan, Borneman, James, Schiestl, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718495/
https://ncbi.nlm.nih.gov/pubmed/23860718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0022
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