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Intestinal mucosal inflammation leads to systemic genotoxicity in mice

Inflammatory bowel disease, including ulcerative colitis and Crohn’s disease, substantially increases the risk of colorectal cancer. However, mechanisms linking mucosal inflammation to the sequence of dysplasia are incompletely understood. While studies have demonstrated oxidative damage to the colo...

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Detalhes bibliográficos
Main Authors: Westbrook, Aya M., Wei, Bo, Braun, Jonathan, Schiestl, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709766/
https://ncbi.nlm.nih.gov/pubmed/19487293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4416
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