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Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia
Hoxa9 is expressed in hematopoietic stem and progenitor cells although this expression is usually diminished as these cells undergo differentiation. In addition, aberrant expression of Hoxa9 is strongly associated with both T-cell and myeloid leukemia in mice and humans. Despite this strong associat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718276/ https://ncbi.nlm.nih.gov/pubmed/23435313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.02.006 |
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