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Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia

Hoxa9 is expressed in hematopoietic stem and progenitor cells although this expression is usually diminished as these cells undergo differentiation. In addition, aberrant expression of Hoxa9 is strongly associated with both T-cell and myeloid leukemia in mice and humans. Despite this strong associat...

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Hlavní autoři: Beachy, Sarah H., Onozawa, Masahiro, Silverman, Deborah, Chung, Yang Jo, Rivera, Mariela Martinez, Aplan, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718276/
https://ncbi.nlm.nih.gov/pubmed/23435313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.02.006
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