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Kinetic response of a photoperturbed allosteric protein
By covalently linking an azobenzene photoswitch across the binding groove of a PDZ domain, a conformational transition, similar to the one occurring upon ligand binding to the unmodified domain, can be initiated on a picosecond timescale by a laser pulse. The protein structures have been characteriz...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718176/ https://ncbi.nlm.nih.gov/pubmed/23818626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306323110 |
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