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Understanding GPCR recognition and folding from NMR studies of fragments

Cotranslational protein folding is a vectorial process, and for membrane proteins, N-terminal helical segments are the first that become available for membrane insertion. While structures of many G-protein coupled receptors (GPCRs) in various states have been determined, the details of their folding...

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Pubblicato in:RSC Adv
Autori principali: Marino, Jacopo, Walser, Reto, Poms, Martin, Zerbe, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society of Chemistry 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935241/
https://ncbi.nlm.nih.gov/pubmed/29732143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ra01520a
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