BET proteins promote efficient murine leukemia virus integration at transcription start sites

The selection of chromosomal targets for retroviral integration varies markedly, tracking with the genus of the retrovirus, suggestive of targeting by binding to cellular factors. γ-Retroviral murine leukemia virus (MLV) DNA integration into the host genome is favored at transcription start sites, b...

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Dettagli Bibliografici
Autori principali: Sharma, Amit, Larue, Ross C., Plumb, Matthew R., Malani, Nirav, Male, Frances, Slaughter, Alison, Kessl, Jacques J., Shkriabai, Nikolozi, Coward, Elizabeth, Aiyer, Sriram S., Green, Patrick L., Wu, Li, Roth, Monica J., Bushman, Frederic D., Kvaratskhelia, Mamuka
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718171/
https://ncbi.nlm.nih.gov/pubmed/23818621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307157110
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