BET proteins promote efficient murine leukemia virus integration at transcription start sites

The selection of chromosomal targets for retroviral integration varies markedly, tracking with the genus of the retrovirus, suggestive of targeting by binding to cellular factors. γ-Retroviral murine leukemia virus (MLV) DNA integration into the host genome is favored at transcription start sites, b...

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Detalhes bibliográficos
Main Authors: Sharma, Amit, Larue, Ross C., Plumb, Matthew R., Malani, Nirav, Male, Frances, Slaughter, Alison, Kessl, Jacques J., Shkriabai, Nikolozi, Coward, Elizabeth, Aiyer, Sriram S., Green, Patrick L., Wu, Li, Roth, Monica J., Bushman, Frederic D., Kvaratskhelia, Mamuka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718171/
https://ncbi.nlm.nih.gov/pubmed/23818621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307157110
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