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Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II
Centrosome reorientation to the immunological synapse maintains the specificity of T-cell effector function by facilitating the directional release of cytokines and cytolytic factors toward the antigen-presenting cell. This polarization response is driven by the localized accumulation of diacylglyce...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718145/ https://ncbi.nlm.nih.gov/pubmed/23818610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306180110 |
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