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Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II

Centrosome reorientation to the immunological synapse maintains the specificity of T-cell effector function by facilitating the directional release of cytokines and cytolytic factors toward the antigen-presenting cell. This polarization response is driven by the localized accumulation of diacylglyce...

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Bibliografski detalji
Glavni autori: Liu, Xin, Kapoor, Tarun M., Chen, James K., Huse, Morgan
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718145/
https://ncbi.nlm.nih.gov/pubmed/23818610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306180110
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