Biomarker Modulation Following Short Term Vorinostat in Women with Newly-Diagnosed Primary Breast Cancer

PURPOSE: Agents that target the epigenome demonstrate activity in breast cancer models. In preclinical studies, the histone deacetylase inhibitor vorinostat induces cell cycle arrest, apoptosis and differentiation. We evaluated biomarker modulation in breast cancer tissues obtained from women with n...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Stearns, Vered, Jacobs, Lisa K., Fackler, MaryJo, Tsangaris, Theodore N., Rudek, Michelle A., Higgins, Michaela, Lange, Julie, Cheng, Zandra, Slater, Shannon A., Jeter, Stacie C., Powers, Penny, Briest, Susanne, Chao, Calvin, Yoshizawa, Carl, Sugar, Elizabeth, Espinoza-Delgado, Igor, Sukumar, Saraswati, Gabrielson, Edward, Davidson, Nancy E.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718062/
https://ncbi.nlm.nih.gov/pubmed/23719261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0033
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki