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Systemic Regulation of the Age-Related Decline of Pancreatic β-Cell Replication

The frequency of pancreatic β-cell replication declines dramatically with age, potentially contributing to the increased risk of type 2 diabetes in old age. Previous studies have shown the involvement of cell-autonomous factors in this phenomenon, particularly the decline of polycomb genes and accum...

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Detalhes bibliográficos
Main Authors: Salpeter, Seth J., Khalaileh, Abed, Weinberg-Corem, Noa, Ziv, Oren, Glaser, Benjamin, Dor, Yuval
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717843/
https://ncbi.nlm.nih.gov/pubmed/23630298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0160
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