Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity

Glioblastoma multiforme (GBM) is the most aggressive brain cancer, and to date, no curative treatment has been developed. In this study, we report that miR-211, a microRNA predicted to target MMP-9, is suppressed in grade IV GBM specimens. Furthermore, we found that miR-211 suppression in GBM involv...

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Bibliographic Details
Main Authors: Asuthkar, Swapna, Velpula, Kiran Kumar, Chetty, Chandramu, Gorantla, Bharathi, Rao, Jasti S.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717804/
https://ncbi.nlm.nih.gov/pubmed/23183822
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