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Urokinase-type Plasminogen Activator Receptor (uPAR)-mediated Regulation of WNT/β-Catenin Signaling Is Enhanced in Irradiated Medulloblastoma Cells

Urokinase plasminogen activator receptor (uPAR) is known to promote invasion, migration, and metastasis in cancer cells. In this report, we showed that ionizing radiation (IR)-induced uPAR has a role in WNT-β-catenin signaling and mediates induction of cancer stem cell (CSC)-like properties in medul...

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Detalhes bibliográficos
Main Authors: Asuthkar, Swapna, Gondi, Christopher S., Nalla, Arun Kumar, Velpula, Kiran Kumar, Gorantla, Bharathi, Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370242/
https://ncbi.nlm.nih.gov/pubmed/22511755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.348888
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