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NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1
The principal Epstein-Barr virus (EBV) oncoprotein, Latent Membrane Protein 1 (LMP1), is expressed in most EBV-associated human malignancies. LMP1 mimics CD40 receptor signaling to provide infected cells with constitutive NF-κB, MAP kinase, IRF7, and PI3 kinase pathway stimulation. EBV-transformed B...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717723/ https://ncbi.nlm.nih.gov/pubmed/23793113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v5061587 |
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