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Thermodynamic Analysis of Protein-Ligand Binding Interactions in Complex Biological Mixtures using the Stability of Proteins from Rates of Oxidation (SPROX) Method

The detection and quantitation of protein-ligand binding interactions is critical in a number of different areas of biochemical research from fundamental studies of biological processes to drug discovery efforts. Described here is a protocol that can be used to identify the protein targets of biolog...

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Main Authors: Strickland, Erin C., Geer, M. Ariel, Tran, Duc T., Adhikari, Jagat, West, Graham M., DeArmond, Patrick D., Xu, Ying, Fitzgerald, Michael C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717606/
https://ncbi.nlm.nih.gov/pubmed/23257983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.146
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