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False Positive Rate Determination of Protein Target Discovery using a Covalent Modification- and Mass Spectrometry-Based Proteomics Platform

[Image: see text] Detection and quantitation of protein-ligand binding interactions is important in many areas of biological research. The Stability of Proteins from Rates of Oxidation (SPROX) technique is an energetics-based technique for identifying the proteins targets of ligands in complex biolo...

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Autori principali: Strickland, Erin C., Geer, M. Ariel, Hong, Jiyong, Fitzgerald, Michael C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880622/
https://ncbi.nlm.nih.gov/pubmed/24114261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-013-0754-2
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