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Adenoviral vector tethering to metal surfaces via hydrolysable cross-linkers for the modulation of vector release and transduction

The use of arterial stents and other medical implants as a delivery platform for surface immobilized gene vectors allows for safe and efficient localized expression of therapeutic transgenes. In this study we investigate the use of hydrolysable cross-linkers with distinct kinetics of hydrolysis for...

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Autors principals: Fishbein, Ilia, Forbes, Scott P., Chorny, Michael, Connolly, Jeanne M., Adamo, Richard F., Corrales, Ricardo, Alferiev, Ivan S., Levy, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717522/
https://ncbi.nlm.nih.gov/pubmed/23777912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.047
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