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Adenoviral vector tethering to metal surfaces via hydrolysable cross-linkers for the modulation of vector release and transduction
The use of arterial stents and other medical implants as a delivery platform for surface immobilized gene vectors allows for safe and efficient localized expression of therapeutic transgenes. In this study we investigate the use of hydrolysable cross-linkers with distinct kinetics of hydrolysis for...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717522/ https://ncbi.nlm.nih.gov/pubmed/23777912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.047 |
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