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Magnetically Responsive Biodegradable Nanoparticles Enhance Adenoviral Gene Transfer in Cultured Smooth Muscle and Endothelial Cells

Replication-defective adenoviral (Ad) vectors have shown promise as a tool for gene delivery-based therapeutic applications. Their clinical use is however limited by therapeutically suboptimal transduction levels in cell types expressing low levels of Coxsackie-Ad receptor (CAR), the primary recepto...

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Detalhes bibliográficos
Main Authors: Chorny, Michael, Fishbein, Ilia, Alferiev, Ivan, Levy, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349935/
https://ncbi.nlm.nih.gov/pubmed/19496618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900017m
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